Featured Scientific Stories

  • Can Repurposed Medicines and Vaccines Change the Course of Alzheimer’s Disease?

    Can Repurposed Medicines and Vaccines Change the Course of Alzheimer’s Disease?

    Researchers are exploring repurposed medicines for Alzheimer’s disease (AD) as cases rise globally. A Delphi consensus identified three priority candidates: the herpes zoster vaccine (Zostavax), sildenafil, and riluzole, based on mechanistic plausibility and safety for older adults. Drug repurposing could offer faster, more accessible treatment options for AD. Read more

  • Are GLP-1 Drugs Quietly Rewriting What We Buy at the Grocery Store?

    Are GLP-1 Drugs Quietly Rewriting What We Buy at the Grocery Store?

    A population-based study examined the impact of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on food purchases among 1,177 adults. Following GLP-1RA initiation, participants showed decreased energy density, sugar, carbohydrates, and ultra-processed foods in purchases, alongside increased protein and unprocessed foods, indicating potential societal shifts in dietary patterns. Read more

  • Can the Liver (GLP-1R agonism) Unlock the Next Leap in Weight-Loss Therapy?

    A preclinical study on diet-induced obese mice found that targeting GLP-1 receptors in the liver enhances weight-loss efficacy of GLP-1 agonists by increasing energy expenditure and reducing food intake. This approach may offer a safer alternative to multi-agonist therapies, avoiding cardiovascular side effects linked to glucagon receptor activation. Read more

  • GLP-1 Medications: Transforming Cardiovascular Care?

    In 2025, evidence highlighted the effectiveness of GLP-1 receptor agonists, such as semaglutide, in reducing cardiovascular risks for adults with type 2 diabetes and high cardiovascular risk. Major trials showed significant reductions in adverse events and mortality, prompting regulatory approvals in the U.S. and updates in the EU regarding their use. Read more

  • Constipation in Diabetes: The Role of GLP-1–Based Therapies

    GLP-1 Special Series By VETTAPHARMA reporter: For millions of adults living with diabetes mellitus, the focus often falls on blood sugar control, cardiovascular health, and neuropathy. Yet a growing body of evidence shows that chronic constipation affects a substantial portion of patients, significantly impacting quality of life. A narrative review published in Nutrients examines mechanisms, diagnosis, and management of constipation in diabetes, providing a comprehensive guide for clinicians and researchers. The review by Fano et al. 2025, analyzed studies involving adults aged 18–75 years with type 1 or type 2 diabetes, noting that type 2 diabetes accounts for over 90%… Read more

  • CAPLYTA® Improves Remission Rates in Major Depression

    CAPLYTA® Improves Remission Rates in Major Depression

    New clinical data from Johnson & Johnson shows that CAPLYTA® (lumateperone) significantly enhances remission rates in adults with major depressive disorder when combined with antidepressants. Evidence from Phase 3 trials reveals nearly twice the likelihood of remission and notable sustained benefits after six months, reinforcing CAPLYTA® as a vital adjunctive treatment. Read more

  • Prenatal Factors Linked to Adult-Onset Multiple Sclerosis Risk

    Prenatal Factors Linked to Adult-Onset Multiple Sclerosis Risk

    A study in JAMA Neurology suggests that prenatal factors may influence the risk of developing multiple sclerosis (MS) later in life. Examining over a million births in Norway, researchers found that maternal diabetes and being large for gestational age increased MS risk, while being small for gestational age appeared protective. Read more

  • Are Weight-Loss Medications a Temporary Fix?

    Are Weight-Loss Medications a Temporary Fix?

    A systematic review in The BMJ examined the long-term effects of weight-loss medications, finding rapid weight regain after discontinuation, approximately 0.4 kg per month, with all lost weight returning within 1.7 years. The results underscore that ongoing treatment and lifestyle changes are vital for sustained weight and health management. Read more